Arginine pyroglutamate is the L-arginine salt of pyroglutamic acid. It is also known as pirglutargine and arginine pidolate.
Arginine pyroglutamate is a delivery form of pyroglutamate. Pyroglutamate is formed in the body by the cyclization of the amino acid glutamic acid and is found naturally in plant and animal products, including the brain. Pyroglutamate is also known as 2-oxo-pyrrolidone carboxylic acid or PCA and 5-oxoproline. Pyroglutamate is an intermediate of the gamma-glutamyl cycle of glutathione synthesis and degradation.