(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol CAS:127852-28-2CAS number : 127852-28-2

Chemical Name : (R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol

Application : Agrochem or Pharmaceutical intermediates

Product Information
Structural Formula
Synonym (R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol
(R)-3,5-Bis(trifluoromethyl)-α-methylbenzyl Alcohol
(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol
Specifications Upon request
Packing See details
Material Safety Data Sheet Upon request
Availability Please visit www.nbinno.com for our official company website or sending email to info@nbinno.com for more information.
Product Description:

CAS No: 127852-28-2
Product Name: (R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol
Other Name:
(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol
(R)-3,5-Bis(trifluoromethyl)-α-methylbenzyl Alcohol
(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol
 
Density: 1.4±0.1 g/cm3
Boiling Point: 175.8±35.0 °C at 760 mmHg
Molecular Formula: C10H8F6O
Molecular Weight: 258.160
Flash Point: 60.1±25.9 °C
Exact Mass: 258.047943
PSA: 20.23000
LogP: 2.81
Vapour Pressure: 0.7±0.4 mmHg at 25°C
Index of Refraction: 1.418
 
Specification
Appearance: White to off white powder
MP: 50℃-54℃
Optical rotation: +19℃- +25℃
Assay: ≥99.0%
Water: ≤0.5%
Single impurity: ≤0.5%
 
Application
Intermediates of Fosaprepitant CAS: 172673-20-0.
Intermediates of Aprepitant CAS: 170729-80-3.
Be used as pharmaceutical intermediate.
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is an intermediate in the synthesis of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
 
Package: 25kg/drum, can also be designed according to customer requirements.
Storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

We have leading technology and rich synthesis experience, and our professional R&D team is currently in the leading position in China.Provide high quality, regulatory compliance products and services to partners and customers.We offer a wide range of custom synthesis and production services for pharmaceutical intermediates, reference compounds and new reagents for pharmaceutical companies, pharmaceutical biotech companies, universities and research institutions.Since the establishment of the company, it has established good and stable cooperative relations with many domestic and foreign pharmaceutical companies.In addition to our core competence in the standard unit operations of organic chemical synthesis, we offer specialised reaction technology, including innovative organometallic synthesis, catalytic transfer hydrogenation and the various operations required for synthesis of chiral compounds.

China supplier of (R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol CAS:127852-28-2,(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol factory,(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol manufacturer and (R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol producer, send us your inquiry of (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol or request COA,MSDS,NMR of (R)-3,5-Bis(trifluoromethyl)-α-methylbenzyl Alcohol.


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